Safety adipic acid is not classified as hazardous for transport. Aa is the key material causing dust explosion in the powdered resin process. Adipic acid or hexanedioic acid is the organic compound with the formula ch 2 4 cooh 2. Adipic acid produced mild to no skin irritation on intact guinea pig skin as a 50% concentration in propylene glycol. Preparation of adipic acid introduction the carboncarbon double bond of an alkene is a site of relatively high electron density and therefore is susceptible to oxidation. Adipic acid has also been incorporated into controlledrelease formulation matrix tablets to obtain phindependent release for both weakly basic and weakly acidic drugs.
Adipic acid exerts a drying action on the skin and may cause dermatitis in humans. Adipic acid product stewardship summary april 12, 2017. Safety data sheet according to 29cfr19101200 and ghs rev. Ags acid original safety msds data material data safety sheet contact telephone. Worldwide demand for adipic acid in 1989 was nearly 2 billion megagrams mg 2 billion tons, with growth continuing at a steady rate. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. They react in this way with all bases, both organic for example, the amines and inorganic. Global adipic acid market is expected to experience significant growth over the next six years on account of increasing industrial applications. Adipic acid 1035% 124049 warning eyes irritant cat. Our team of scientists has experience in all areas of research including life science, material science, chemical synthesis, chromatography, analytical and many others. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Adipic acid product stewardship summary, version 3. Adipic acid, hoocch 2 4 cooh, is a white crystalline solid used primarily in the manufacture of nylon6,6 polyamide.
Adipic acid aa and pterephthalic acid pta were the bulk raw materials used in the powdered resin manufacturing process. Adipic acid is present in some plants and is a chemical in tobacco and tobacco smoke. From an industrial perspective, it is the most important dicarboxylic acid. Entry into the bloodstream, through, for example, cuts, abrasions or lesions, may. Carboxylic acids donate hydrogen ions if a base is present to accept them. Ascend ships adipic acid in a variety of package sizes, including rail cars, tank trucks, super sacks and 50pound bags, via our established, efficient global distribution network. Conventionally it was manufactured from petrochemicals but in recent days it can be synthesized from renewable substrates by means of biological methods. The most important product manufactured from adipic acid. Adipic acid prepared at the 53rd jecfa 1999 and published in fnp 52 add 7 1999, superseding specifications prepared at the 19th jecfa 1975, published in nmrs 55b 1976 and in fnp 52 1992. Our msds database is an easy to use, do it yourself tool, and best of all. Exposure controlspersonal protection control parameters. Adipic acid market global adipic acid industry growth, size, share, analysis and forecast report. The k st values of aa and pta were 98 and 59 m bars. Adipic acid is on the hazardous substance list because it.
Scientific opinion on the safety assessment of the substance. Assessment of dust explosion with adipic acid and p. Emergency eye wash fountains and safety showers should be available in the immediate vicinity of use or handling. The direct synthesis of adipic acid from cyclohexene and hydrogen peroxide by a continuous microflow process minjing shang eindhoven university of technology, 2016 a catalogue record is available from the eindhoven university of technology library isbn. If swallowed never give anything by mouth to an unconscious person. Adipic acid market analysis, market size, application.
Ascend is the only largescale producer of foodgrade adipic acid in the world. Adipic acid is a basic chemical but is also used in consumer products. Adipic acid in the urine and in the blood is typically exogenous in origin and is a good biomarker of jello consumption. Organic 2 lab report 4 oxidaion cyclohexanone to adipic acid. Read this document completely, and then answer the prelab questions below. In this lesson, the main focal point will be on an organic compound known as adipic acid. Adipic acid basf brenntag product information page. Adipic acid is not expected to volatilize from dry soil surfaces based on its extrapolated vapor pressure.
It is one of the most important monomers in the polymer industry. Chem 321 oxidation of cyclohexene to 1,6hexanedioic acid. A onepot oxidation from cyclohexane to adipic acid has been developed, catalyzed by fe. Safety data sheet adipic acid dihydrazide date prepared. In case of eye contact flush eyes with water as a precaution. Biodegradability screening tests indicate that adipic acid is readily biodegradable. Cyclohexanone to adipic acid organic chemistry ii section 01 dr. Administration of adipic acid to experimental animals has produced patchy. H 319 sodium carbonate 212% 497198 warning eyes irritant cat. This is a quantitative reaction that converts a liquid cyclohexanone into a solid adipic acid.
Inhalation of dust may irritate the respiratory tract. Adi 05 mgkg bw, established at the 21st jecfa in 1977. Adipic acid market global industry analysis, size and. Adipic acid is a straightchain aliphatic dicarboxylic acid, commonly used in the manufacturing of nylon6,6 and plasticizers. Pdf lignin is an alkylaromatic polymer present in plant cell walls for defense, structure, and water transport. They react in this way with all bases, both organic for example, the amines. The adipic acid market can be segmented in the basis of. Adipic acid has very low acute toxicity in rats with an ld50 5000 mgkg. The result is an odorless white crystalline powder with a slightly acidic taste.
Our topics of discussion will include the structure, uses, and hazards associated with adipic acid. The chemicals segment focuses on maintaining and developing basfs production verbund. Under the mandatory reporting of greenhouse gases ghgs rule, owners or operators of facilities that produce adipic acid as defined below must report emissions from adipic acid production processes and. The main success factors for this segment are operational and technological excellence, scale. Adipic acid is an indirect food additive polymer for use as a basic component of single and repeated use food contact surfaces. Based on animal data, this material is presumed to be only slightly toxic. Basfs unique verbund system of highly integrated production sites offers substantial competitive advantages. Adipic acid msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents. The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the. An 84% conversion of adipic acids carbon content to carbon dioxide was observed after 30 days aerobic incubation in soil biometer flasks at. Find patient medical information for adipic acid on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Adipic acid is a commercially important chemical used during the production of nylon, plastics, lubricants, adhesives, and polyurethane foam.
Avoid creating a dust cloud in handling, transfer and clean up. Adipic acid material safety data sheet cas no 124049 sds. View lab report organic 2 lab report 4 oxidaion cyclohexanone to adipic acid from biol 648 at benedict college. Clean synthesis of adipic acid from cyclohexene in.
Physical and chemical properties molecular formula hooc. Since 1981 and still going strong the ecem group is more as 37 years active and we have become the leading distributor of acrylic and methacrylic monomers with bulk storage tanks and supplying bulk in dedicate tankers, totes and drums. Ingestion of large amounts may cause gastrointestinal irritation. In industry, adipic acid is mainly produced by oxidation of cyclohexane with air and nitric acid following a homogeneous twostep route. Adipic acid occurs naturally in living cells beets and sugar cane, but is commercially prepared from the oxidation of cyclohexanol by concentrated nitric acid. General pags purified mixture of adipicglutaricsuccinic acids cas see below. The direct synthesis of adipic acid from cyclohexene and. Pdf adipic acid production from lignin researchgate. Adipic acid cas no 124049 material safety data sheet. Their reactions with bases, called neutralizations, are accompanied by. On a balance, tare a small test tube that has been placed in an empty 50 to 100ml beaker for stabilization.
Preparation of adipic acid from cyclohexene in this laboratory period the cyclohexene supposedly prepared in the previous experiment is oxidized to adipic acid. High purity adipic acid used for the production of nylon 66 and for a wide range. The type of oxidation product obtained is dependent upon the reagents and conditions used to affect the oxidation of the alkene figure 1. Adipic acid cas no 124049 material safety data sheet sds msds.
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